TOR1B anticorps (AA 281-336) (Cy5.5)
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- Antigène Voir toutes TOR1B Anticorps
- TOR1B (Torsin Family 1, Member B (Torsin B) (TOR1B))
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Épitope
- AA 281-336
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TOR1B est conjugé à/à la Cy5.5
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Dog,Cow,Sheep,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Torsin B
- Isotype
- IgG
- Top Product
- Discover our top product TOR1B Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- TOR1B (Torsin Family 1, Member B (Torsin B) (TOR1B))
- Abstract
- TOR1B Produits
- Synonymes
- anticorps MGC82811, anticorps tor1a, anticorps 2610016F05Rik, anticorps DQ1, anticorps torsinB, anticorps torsin family 1, member B (torsin B) L homeolog, anticorps torsin family 1, member B (torsin B), anticorps torsin family 1 member B, anticorps torsin family 1, member B, anticorps tor1b.L, anticorps tor1b, anticorps TOR1B, anticorps Tor1b
- Sujet
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Synonyms: DQ1, Tor1b, Torsin 1B, TOR1B, FKSG18, Torsin family 1 member B, TOR1B_HUMAN.
Background: TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family. Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins. Via its ability to regulate protein folding, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development. TorsinB contains two PKC (protein kinase C) phosphorylations sites, one ATP binding domain and several conserved cysteines and shares 69 % amino acid identity with TorsinA, a related family member. Defects in the gene encoding TorsinB are associated with torsion dystonia, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body.
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