WWC1 anticorps (AA 351-450) (Cy3)
-
- Antigène Voir toutes WWC1 Anticorps
- WWC1 (WW and C2 Domain Containing 1 (WWC1))
-
Épitope
- AA 351-450
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp WWC1 est conjugé à/à la Cy3
-
Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Cow,Sheep,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human KIBRA
- Isotype
- IgG
- Top Product
- Discover our top product WWC1 Anticorps primaire
-
-
- Indications d'application
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- WWC1 (WW and C2 Domain Containing 1 (WWC1))
- Autre désignation
- KIBRA (WWC1 Produits)
- Synonymes
- anticorps CG12600, anticorps CG33967, anticorps CG7552, anticorps Dmel\\CG33967, anticorps Kibra, anticorps ORE-2, anticorps RE26350, anticorps kib, anticorps l(3)02404, anticorps l(3)j5C3, anticorps l(3)neo42, anticorps HBEBP3, anticorps HBEBP36, anticorps KIBRA, anticorps AA408228, anticorps AU017197, anticorps BC037006, anticorps mKIAA0869, anticorps CG33967 gene product from transcript CG33967-RB, anticorps WW and C2 domain containing 1, anticorps WW, C2 and coiled-coil domain containing 1, anticorps kibra, anticorps WWC1, anticorps Wwc1
- Sujet
-
Synonyms: KIBRA, HBEBP3, HBEBP36, MEMRYQTL, PPP1R168, Protein KIBRA, HBeAg-binding protein 3, Kidney and brain protein, WW domain-containing protein 1, WWC1, KIAA0869
Background: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.
- ID gène
- 23286
- UniProt
- Q8IX03
-