RNF146 anticorps (AA 95-160) (Cy5)

N° du produit ABIN1410526

Détail du produit anti-RNF146 anticorps (Cy5)

Antigène: RNF146 (Ring Finger Protein 146 (RNF146))

Épitope: AA 95-160

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF146 est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RNF146

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RNF146

Antigène: RNF146 (Ring Finger Protein 146 (RNF146))

Autre désignation: RNF146 (RNF146 Produits)

Synonymes: anticorps RP3-351K20.1, anticorps dJ351K20.1, anticorps 2610509H23Rik, anticorps Iduna, anticorps RNF146, anticorps rnf146, anticorps dactylidin, anticorps wu:fi29e08, anticorps zgc:55909, anticorps ring finger protein 146, anticorps RING finger protein 146, anticorps ring finger protein 146 S homeolog, anticorps RNF146, anticorps Rnf146, anticorps rn146, anticorps rnf146.S, anticorps rnf146

Sujet:

Synonyms: Dactylidin, dJ351K20.1, DKFZP434O1427, E3 ubiquitin-protein ligase rnf146, RING finger protein 146, RN146_HUMAN, RNF 146, Rnf146, RP3 351K20.1.

Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF146 (RING finger protein 146), also known as Dactylidin, is a 359 amino acid protein that contains one RING-type zinc finger and one WWE domain. Via its RING-type zinc finger, RNF146 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF146 are associated with Alzheimer's disease (AD) and may lead to a higher risk of breast cancer. Two isoforms of RNF146 exist due to alternative splicing events.