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ITM2C anticorps (AA 3-88) (Cy5)

ITM2C Reactivité: Humain WB, IF (p), IF (cc) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN1411636
  • Antigène Voir toutes ITM2C Anticorps
    ITM2C (Integral Membrane Protein 2C (ITM2C))
    Épitope
    • 14
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-88
    Reactivité
    • 35
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 33
    • 2
    Lapin
    Clonalité
    • 35
    Polyclonal
    Conjugué
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ITM2C est conjugé à/à la Cy5
    Application
    • 33
    • 17
    • 12
    • 12
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human ITM2C
    Isotype
    IgG
    Top Product
    Discover our top product ITM2C Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ITM2C (Integral Membrane Protein 2C (ITM2C))
    Autre désignation
    ITM2C (ITM2C Produits)
    Synonymes
    anticorps 3110038L02Rik, anticorps BRI3, anticorps Bricd2c, anticorps E25, anticorps E25C, anticorps ITM3, anticorps BRICD2C, anticorps fj35c02, anticorps itm2c, anticorps wu:fj35c02, anticorps zgc:66349, anticorps wu:fj52a04, anticorps zgc:92783, anticorps integral membrane protein 2C, anticorps integral membrane protein 2Cb, anticorps integral membrane protein 2Ca, anticorps Itm2c, anticorps ITM2C, anticorps itm2cb, anticorps itm2ca
    Sujet

    Synonyms: BRI3, BRICD2C, BRICHOS domain containing 2C, Cerebral protein 14, CT-BRI3, E25, E25C , Integral membrane protein 2C, Integral membrane protein 3, Itm2c, ITM2C_HUMAN, ITM3 antibodyNPD018, Transmembrane protein BRI3.

    Background: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.

    ID gène
    81618
    UniProt
    Q9NQX7
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