GARP anticorps (AA 856-960) (Cy5)
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- Antigène Voir toutes GARP (CNGB1) Anticorps
- GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))
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Épitope
- AA 856-960
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GARP est conjugé à/à la Cy5
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Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Homologie
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CNGB1
- Isotype
- IgG
- Top Product
- Discover our top product CNGB1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))
- Autre désignation
- CNG4/GARP (CNGB1 Produits)
- Synonymes
- anticorps CNCG2, anticorps CNCG3L, anticorps CNCG4, anticorps CNG4, anticorps CNGB1B, anticorps GAR1, anticorps GARP, anticorps RCNC2, anticorps RCNCb, anticorps RCNCbeta, anticorps RP45, anticorps Gm1959, anticorps Cngb1b, anticorps CNGB1, anticorps si:ch211-160j6.1, anticorps cyclic nucleotide gated channel beta 1, anticorps cyclic nucleotide gated channel beta 1a, anticorps CNGB1, anticorps Cngb1, anticorps cngb1a
- Sujet
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Synonyms: CNCG2, CNCG3L, CNCG4, CNG 4, CNG-4, CNG channel 4, CNG channel beta 1, CNG4, CNGB 1, CNGB1, CNGB1B, Cyclic nucleotide gated cation channel 4, Cyclic nucleotide gated cation channel, Cyclic nucleotide gated cation channel beta 1, Cyclic nucleotide gated cation channel gamma, Cyclic nucleotide gated cation channel modulatory subunit, Cyclic nucleotide gated channel photoreceptor cGMP gated 3 gamma like, Cyclic nucleotide gated channel beta 1, GAR1, Glutamic acid rich protein, RCNC2, RCNCb, RCNCbeta, RP45, CNGB1_HUMAN.
Background: Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1,2). The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1,2). The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels (1,2). CNG channels are essential components of olfactory and visual transduction (1,2). In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP (1-3). In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP (1-3). CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2,3). CNG channels have been implicated in other areas (4-6). CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4). CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland (5). CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6).
- UniProt
- Q14028
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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