MMS19 anticorps (AA 851-950) (Cy3)
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- Antigène Voir toutes MMS19 Anticorps
- MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
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Épitope
- AA 851-950
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MMS19 est conjugé à/à la Cy3
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human MMS 19
- Isotype
- IgG
- Top Product
- Discover our top product MMS19 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
- Autre désignation
- MMS19 (MMS19 Produits)
- Synonymes
- anticorps MET18, anticorps MMS19L, anticorps hMMS19, anticorps 2410001K24Rik, anticorps 2610042O15Rik, anticorps AI316855, anticorps C79368, anticorps C86341, anticorps Mms19l, anticorps mms19, anticorps mms19l, anticorps MMS19 homolog, cytosolic iron-sulfur assembly component, anticorps MMS19 (MET18 S. cerevisiae), anticorps MMS19 homolog, cytosolic iron-sulfur assembly component L homeolog, anticorps MMS19, anticorps Mms19, anticorps mms19.L
- Sujet
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Synonyms: MET18, MMS19L, hMMS19, MMS19 nucleotide excision repair protein homolog, MET18 homolog, MMS19-like protein, MMS19
Background: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
- ID gène
- 64210
- UniProt
- Q96T76
- Pathways
- Nuclear Hormone Receptor Binding
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