RANBP2 anticorps (Cy5)

N° du produit ABIN1419930

Détail du produit anti-RANBP2 anticorps (Cy5)

Antigène: RANBP2 (RAN Binding Protein 2 (RANBP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANBP2 est conjugé à/à la Cy5

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RanBP2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RANBP2

Antigène: RANBP2 (RAN Binding Protein 2 (RANBP2))

Autre désignation: RanBP2 (RANBP2 Produits)

Synonymes: anticorps ANE1, anticorps IIAE3, anticorps NUP358, anticorps TRP1, anticorps TRP2, anticorps A430087B05Rik, anticorps AI256741, anticorps RGD1560047, anticorps RANBP2, anticorps ane1, anticorps nup358, anticorps trp1, anticorps trp2, anticorps RAN binding protein 2, anticorps E3 SUMO-protein ligase RanBP2, anticorps RANBP2, anticorps Ranbp2, anticorps LOC474539, anticorps ranbp2, anticorps LOC100511376

Sujet:

Synonyms: Nuclear pore complex protein Nup358, Nucleoporin 358, Nucleoporin Nup358, NUP358, P270, RAN binding protein 2, Ran-binding protein 2, RANBP2, RBP2_HUMAN, Transformation related protein 2, TRP 1, TRP 2, TRP1, TRP2, 358 kDa nucleoporin, E3 SUMO-protein ligase RanBP2.

Background: The nuclear pore complex protein, Ran-binding protein 2 (Ran BP-2 or Nup358), contains four Ran-binding domains. Ran BP-2 is a large scaffold cyclophilin-related protein expressed in photoreceptor cells. Ran BP-2 localization at cytoplasmic fibrils emanating from the nuclear pore complex and interaction with the Ran-GTPase support its role in nucleocytoplasmic transport processes. In humans, the Ran BP-2 gene is partially duplicated in a gene cluster and lies in a hot spot for recombination on chromosome 2q. This genetic heterogeneity renders further significance of this genomic region in human disease due to its possible involvement in genetically linked disorders such as juvenile nephronophthisis, congenital hepatic fibrosis and chorioretinal dysplasia.

ID gène: 5903

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus