C17orf49 anticorps (HRP)

N° du produit ABIN1421686

Détail du produit anti-C17orf49 anticorps (HRP)

Antigène: C17orf49 (Chromosome 17 Open Reading Frame 49 (C17orf49))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C17orf49 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human C17orf49

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur C17orf49

Antigène: C17orf49 (Chromosome 17 Open Reading Frame 49 (C17orf49))

Autre désignation: C17orf49 (C17orf49 Produits)

Synonymes: anticorps BAP18, anticorps HEPIS, anticorps bap18, anticorps C17orf49, anticorps MGC145240, anticorps 1110020A23Rik, anticorps AL033328, anticorps AU045833, anticorps Bap18, anticorps RP23-198E14.7, anticorps chromosome 17 open reading frame 49, anticorps chromosome 17 open reading frame 49 S homeolog, anticorps chromosome 19 open reading frame, human C17orf49, anticorps chromosome 16 open reading frame, human C17orf49, anticorps RIKEN cDNA 0610010K14 gene, anticorps similar to RIKEN cDNA 1110020A23, anticorps C17orf49, anticorps c17orf49.S, anticorps C19H17orf49, anticorps C16H17orf49, anticorps c17orf49, anticorps 0610010K14Rik, anticorps RGD1308134

Sujet:

Synonyms: Bap18, BAP18_HUMAN, BPTF-associated protein of 18 kDa, Chromatin complexes subunit BAP18, Chromosome 17 open reading frame 49, Hypothetical protein LOC124944, MGC49942, Uncharacterized potential DNA binding protein C17orf49.

Background: C17orf49 is a 172 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5 % of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

ID gène: 124944