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C18orf1 anticorps (AA 1-50) (Cy5.5)

C18orf1 Reactivité: Humain, Souris, Rat WB, IF (p) Hôte: Lapin Polyclonal Cy5.5
N° du produit ABIN1421749
  • Antigène Voir toutes C18orf1 Anticorps
    C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
    Épitope
    • 14
    • 2
    • 1
    • 1
    AA 1-50
    Reactivité
    • 22
    • 20
    • 20
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 20
    • 2
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp C18orf1 est conjugé à/à la Cy5.5
    Application
    • 22
    • 12
    • 3
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human C18orf1
    Isotype
    IgG
    Top Product
    Discover our top product C18orf1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
    Autre désignation
    C18orf1 (C18orf1 Produits)
    Synonymes
    anticorps C18orf1, anticorps 8230401C20Rik, anticorps A430083H02, anticorps A430108L08Rik, anticorps D18Ertd653e, anticorps D330030L18Rik, anticorps low density lipoprotein receptor class A domain containing 4, anticorps LDLRAD4, anticorps Ldlrad4
    Sujet

    Synonyms: C18orf1, Low-density lipoprotein receptor class A domain-containing protein 4, LDLRAD4

    Background: Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.

    ID gène
    753
    UniProt
    O15165
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