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IFI35 anticorps (PE-Cy7)

IFI35 Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien WB Hôte: Lapin Polyclonal PE-Cy7
N° du produit ABIN1437241
  • Antigène Voir toutes IFI35 Anticorps
    IFI35 (Interferon-Induced Protein 35 (IFI35))
    Reactivité
    Humain, Souris, Rat, Porc, Boeuf (Vache), Chien
    Hôte
    • 33
    • 9
    Lapin
    Clonalité
    • 36
    • 6
    Polyclonal
    Conjugué
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IFI35 est conjugé à/à la PE-Cy7
    Application
    • 33
    • 17
    • 16
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human IFI35
    Isotype
    IgG
    Top Product
    Discover our top product IFI35 Anticorps primaire
  • Indications d'application
    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    IFI35 (Interferon-Induced Protein 35 (IFI35))
    Autre désignation
    IFI35 (IFI35 Produits)
    Synonymes
    anticorps IFI35, anticorps IFP35, anticorps 2010008K16Rik, anticorps AW986054, anticorps ifi-35, anticorps interferon induced protein 35, anticorps interferon-induced protein 35, anticorps IFI35, anticorps ifi35, anticorps Ifi35
    Sujet

    Synonyms: I 35, i-35, I35, P 35, P35, IN35, IN35_HUMAN, Interferon induced 35 kDa protein, Interferon-induced 35 kDa protein.

    Background: The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-? IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-?signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-? Two isoforms of IFI-35 exist due to alternative splicing events.

    Poids moléculaire
    31kDa
    ID gène
    3430
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