RAB27A anticorps (C-Term)

N° du produit ABIN1440000

Détail du produit anti-RAB27A anticorps

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Mouton, Boeuf (Vache), Chévre, Cheval, Chien, Lapin, Cobaye, Singe, Poulet, Porc, Cat, Âne, Hamster, Avian

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB27A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: Detects Rab27a by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab27a. This antibody also recognizes Rab27b protein.

Attributs du produit: RAB27A, member RAS oncogene family

Purification: epitope affinity purified

Immunogène: Purified recombinant peptide derived from within residues 120 aa to the C-terminus of mouse Rab27a produced in E. coli.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Polyclonal antibody supplied as a 200 µL (1 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.

Références pour anticorps anti-RAB27A (ABIN1440000)

Alzahofi, Welz, Robinson, Page, Briggs, Stainthorp, Reekes, Elbe, Straub, Kallemeijn, Tate, Goff, Sviderskaya, Cantero, Montoliu, Nedelec, Miles, Bailly, Kerkhoff, Hume: "Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins." dans: Nature communications, Vol. 11, Issue 1, pp. 3495, (2020) (PubMed).

Pelkonen, Reinisalo, Morin-Picardat, Kidron, Urtti: "Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium." dans: PLoS ONE, Vol. 11, Issue 8, pp. e0160352, (2017) (PubMed).

Reichhart, Markowski, Ishiyama, Wagner, Crespo-Garcia, Schorb, Ramalho, Milenkovic, Föckler, Seabra, Strauß: "Rab27a GTPase modulates L-type Ca2+ channel function via interaction with the II-III linker of CaV1.3 subunit." dans: Cellular signalling, Vol. 27, Issue 11, pp. 2231-40, (2016) (PubMed).

Détails sur RAB27A

Antigène: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Autre désignation: Rab27a (RAB27A Produits)

Synonymes: anticorps MGC80943, anticorps RAB27A, anticorps gs2, anticorps ram, anticorps rab27, anticorps MGC89827, anticorps hst18676, anticorps zgc:114135, anticorps GS2, anticorps HsT18676, anticorps RAB27, anticorps RAM, anticorps 2210402C08Rik, anticorps 2410003M20Rik, anticorps 4933437C11Rik, anticorps ash, anticorps RAB27A, member RAS oncogene family L homeolog, anticorps RAB27A, member RAS oncogene family, anticorps RAB27A, member RAS oncogene family S homeolog, anticorps rab27a.L, anticorps RAB27A, anticorps rab27a, anticorps rab27a.S, anticorps Rab27a

Sujet: Rab27a belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and involved in lysosome-related vesicle transport and small GTPase mediated signal transduction.
Synonyms: GS2, GTP-binding protein Ram, rab-27, ras-related protein Rab-27A, RAB27, RAM.
Ensembl identifier: ENSG00000069974

Pathways: Peptide Hormone Metabolism