SF3B1 anticorps
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- Antigène Voir toutes SF3B1 Anticorps
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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Reactivité
- Humain, Souris, Hamster
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SF3B1 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody reacts with Sap155.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse, Hamster
- Purification
- Protein A agarose
- Immunogène
- Recombinant mouse Sap155
- Clone
- 1A5
- Isotype
- IgG2b
- Top Product
- Discover our top product SF3B1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
- Autre désignation
- SF3B1 / SAP155 (SF3B1 Produits)
- Synonymes
- anticorps Cus1, anticorps SAP145, anticorps SF3B145, anticorps SF3b1, anticorps SF3b150, anticorps Hsh155, anticorps MDS, anticorps PRP10, anticorps PRPF10, anticorps SAP155, anticorps SF3b155, anticorps 155kDa, anticorps 2810001M05Rik, anticorps AA409119, anticorps Prp10, anticorps TA-8, anticorps Targ4, anticorps hsh155, anticorps prp10, anticorps prpf10, anticorps sap155, anticorps SF3B1, anticorps Sap155, anticorps wu:fb99f09, anticorps splicing factor 3b subunit 2, anticorps splicing factor 3b subunit 1, anticorps splicing factor 3b, subunit 1, anticorps splicing factor 3b subunit 1 S homeolog, anticorps SF3B2, anticorps SF3B1, anticorps Sf3b1, anticorps sf3b1.S, anticorps sf3b1
- Sujet
- SF3 is a U2 snRNP-associated protein complex essential for spliceosome assembly and splicing catalysis of the major spliceosome. SF3 contains the Spliceosome-Associated Proteins, SAP 49, 130, 145, and 155. SAP155/Sf3b1 is an essential subunit of the U2 snRNP for mRNA splicing and has also been identified in the minor (U12-dependent) spliceosome. SAP155 interacts with the mammalian PcG (Polycomb group) proteins, Mel18 and Ring1B by the yeast two-hybrid system. SAP155 contains numerous Cdk consensus phosphorylation sites in its N terminus and is phosphorylated prior to catalytic step II of the splicing pathway. SAP155 serves as a substrate for cyclin E-cdk2 in vitro, suggesting that pre-mRNA splicing may be linked to the cell cycle machinery in mammalian cells.Synonyms: Pre-mRNA-splicing factor SF3b 155 kDa subunit, SAP 155, SAP-155, SF3b155, Spliceosome-associated protein 155, Splicing factor 3B subunit 1
- ID gène
- 23451
- NCBI Accession
- NP_036565
- UniProt
- O75533
- Pathways
- Chromatin Binding
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