CYBA anticorps (FITC)
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- Antigène Voir toutes CYBA Anticorps
- CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CYBA est conjugé à/à la FITC
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Application
- Flow Cytometry (FACS)
- Specificité
- This antibody reacts with an extracellular epitope of gp91phox. The antibody recognizes the epitope in the native conformation. This antibody reacts with Flavocytochrome b558 on flow cytometry.
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Protein A agarose
- Immunogène
- Human cytochrome b rich fraction
- Clone
- 7D5
- Isotype
- IgG1
- Top Product
- Discover our top product CYBA Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS, 0.09 % NaN3, 1 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8 °C.
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- Antigène
- CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
- Autre désignation
- Cytochrome B-245 Light Chain (CYBA Produits)
- Synonymes
- anticorps zgc:66077, anticorps MGC80750, anticorps CYBA, anticorps p22-phox, anticorps p22phox, anticorps p22-PHOX, anticorps b558, anticorps nmf333, anticorps P22-PHOX, anticorps cytochrome b-245, alpha polypeptide, anticorps cytochrome b-245 alpha polypeptide L homeolog, anticorps cytochrome b-245 alpha polypeptide, anticorps cytochrome b-245 light chain-like, anticorps cytochrome b-245 alpha chain, anticorps p22-phox, anticorps cyba, anticorps cyba.L, anticorps CYBA, anticorps LOC101328418, anticorps Cyba
- Sujet
- The NADPH oxidase is a multicomponent enzyme that transfers electrons from NADPH to O2 to generate superoxide (O2 -), a key part of the phagocytic or neutrophilic respiratory burst response. Flavocytochrome b558 is the catalytic component of the phagocyte NADPH oxidase. It is a transmembrane heterodimer composed of a large glycoprotein, gp91phox (PHagocyte OXidase) and a smaller protein, p22phox. Upon cell stimulation, flavocytochrome b558 assembles with p67phox, p47phox, and the GTP-binding protein Rac and becomes activated to generate O2 -. Mutations in gp91phox, p22phox, or other components of the NADPH oxidase can result in chronic granulomatous disease, which is associated with significant morbidity and mortality due to a predisposition to recurrent bacterial and fungal infections.Synonyms: CYBA, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox
- ID gène
- 1535
- NCBI Accession
- NP_000092
- UniProt
- P13498
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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