DLK1 anticorps
-
- Antigène Voir toutes DLK1 Anticorps
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
-
Reactivité
- Souris
-
Hôte
- Rat
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp DLK1 est non-conjugé
-
Application
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- This antibody reacts with Dlk.
- Réactivité croisée (Details)
- Species reactivity (tested):Mouse.
- Purification
- Protein G Agarose Chromatography of hybridoma supernatant
- Immunogène
- Pref-1-Fc protein
- Clone
- 24-11-14
- Isotype
- IgG1
- Top Product
- Discover our top product DLK1 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % Glycerol, pH 7.2, None
- Agent conservateur
- Azide free
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Upon receipt, store (in aliqouts) at -20 °C.
-
- Antigène
- DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))
- Autre désignation
- DLK1 (DLK1 Produits)
- Sujet
- Delta like protein (Dlk), also known as Preadipocyte factor-1 (Pref-1) or zona glomerulosa-specific factor (ZOG), is an EGF-like transmembrane protein expressed preadipocytes but not in mature adipocytes. It is highly expressed in fetal liver, the adrenal gland, and placenta, as well as some neuroendocrine tumors and small cell lung carcinomas, where it plays a role in differentiation and proliferation. Dlk positively and negatively regulates adipocyte differentiation via at least four major variants (45-60 kDa) of Dlk generated by alternatively splicing. Constitutive expression of Dlk inhibits adipogenesis, but insulin or insulin like growth factor-1 (IGF-1) can circumvent this inhibition. Regulated processing of Dlk releases a 50 kDa soluble form that was previously characterized as Fetal Antigen-1, a protein involved in pancreatic island cell differentiation.Synonyms: DLK, DLK-1, PREF1, Preadipocyte factor 1, Protein delta homolog 1, pG2
- ID gène
- 13386
- NCBI Accession
- NP_034182
- UniProt
- Q09163
-