ATG7 anticorps (AA 501-531)
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- Antigène Voir toutes ATG7 Anticorps
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
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Épitope
- AA 501-531
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ATG7 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Purification
- Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
- Immunogène
- KLH conjugated synthetic peptide between 501~531 amino acids surrounding amino acid R509 of Human APG7L Genename: ATG7
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ATG7 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
- Autre désignation
- APG7L / ATG7 (ATG7 Produits)
- Synonymes
- anticorps APG7-LIKE, anticorps APG7L, anticorps GSA7, anticorps D8, anticorps UBA1B, anticorps UBE1L, anticorps UBE2, anticorps Ube1l, anticorps 1300004C08Rik, anticorps AO090001000744, anticorps atg7, anticorps 1810013K23Rik, anticorps Agp7, anticorps Apg7l, anticorps Atg7l, anticorps ATAPG7, anticorps ATATG7, anticorps ATG7, anticorps AUTOPHAGY 7, anticorps AUTOPHAGY-RELATED 7, anticorps K15I22.10, anticorps K15I22_10, anticorps autophagy related 7, anticorps ubiquitin like modifier activating enzyme 7, anticorps ubiquitin-like modifier activating enzyme 7, anticorps autophagy-related protein 7, anticorps Autophagy-related protein 7, anticorps Apg7p, anticorps ThiF family protein, anticorps ubiquitin-like conjugating enzyme Atg7, anticorps ATG7, anticorps UBA7, anticorps Uba7, anticorps ANI_1_3368024, anticorps AOR_1_1338164, anticorps PTRG_02236, anticorps PAAG_00287, anticorps PITG_12537, anticorps atg7, anticorps Atg7, anticorps APG7
- Sujet
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG7 functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.Synonyms: APG7-like, Autophagy-related protein 7, Ubiquitin-activating enzyme E1-like protein
- Poids moléculaire
- 77960 Da
- ID gène
- 10533
- NCBI Accession
- NP_001129503
- Pathways
- Response to Water Deprivation, Autophagy
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