PRC1 anticorps (Middle Region)

N° du produit ABIN1449936

Détail du produit anti-PRC1 anticorps

Antigène: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRC1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid synthetic peptide near the center of Human PRC1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PRC1

Antigène: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Autre désignation: PRC1 (PRC1 Produits)

Synonymes: anticorps cb212, anticorps prc1, anticorps prc1l, anticorps zgc:55982, anticorps zgc:86918, anticorps MGC68845, anticorps zgc:55664, anticorps ase1, anticorps ASE1, anticorps D7Ertd348e, anticorps protein regulator of cytokinesis 1, anticorps protein regulator of cytokinesis 1a, anticorps protein regulator of cytokinesis 1 S homeolog, anticorps protein regulator of cytokinesis 1b, anticorps PRC1, anticorps prc1a, anticorps prc1.S, anticorps prc1b, anticorps CNC07120, anticorps prc1, anticorps Prc1

Sujet: PRC1 (Protein Regulator of Cytokinesis 1) is a key regulator of cytokinesis and has been identified as a substrate for several cyclin-dependent kinases (CDKs). High levels of PRC1 expression occurs during S and G2/M and drops dramatically after mitosis exit and G1 entry. It is located in the nucleus during interphase and binds to the midzone of mitotic spindles during anaphase and is localized to the cell midbody during cytokinesis. Depletion of PRC1 has been shown to prevent cellular cleavage, but it has no effect on nuclear division, demonstrating the importance of PRC1 in mitosis.Synonyms: ASE1, Protein regulator of cytokinesis 1

ID gène: 9055

NCBI Accession: NP_003972