CRIM1 anticorps (C-Term)

N° du produit ABIN1449941

Détail du produit anti-CRIM1 anticorps

Antigène: CRIM1 (Cysteine Rich Transmembrane BMP Regulator 1 (Chordin-Like) (CRIM1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRIM1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid synthetic peptide near the carboxy terminus of Human CRIM1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CRIM1

Antigène: CRIM1 (Cysteine Rich Transmembrane BMP Regulator 1 (Chordin-Like) (CRIM1))

Autre désignation: CRIM1 (CRIM1 Produits)

Synonymes: anticorps CRIM1, anticorps AU015004, anticorps wu:fc29f08, anticorps CRIM-1, anticorps S52, anticorps cysteine rich transmembrane BMP regulator 1, anticorps cysteine rich transmembrane BMP regulator 1 (chordin like), anticorps cysteine rich transmembrane BMP regulator 1 (chordin-like), anticorps CRIM1, anticorps Crim1, anticorps crim1

Sujet: CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.Synonyms: CRIM-1, Cysteine-rich motor neuron 1 protein, S52

ID gène: 51232

NCBI Accession: NP_057525

Pathways: Growth Factor Binding