ZFYVE21 anticorps (N-Term)

N° du produit ABIN1449943

Détail du produit anti-ZFYVE21 anticorps

Antigène: ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))

Épitope: N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZFYVE21 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid synthetic peptide near the amino terminus of Human ZF21

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ZFYVE21

Antigène: ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))

Autre désignation: ZFYVE21 (ZFYVE21 Produits)

Synonymes: anticorps ZF21, anticorps 1110013H04Rik, anticorps AW558780, anticorps C85416, anticorps zinc finger FYVE-type containing 21, anticorps zinc finger, FYVE domain containing 21, anticorps ZFYVE21, anticorps Zfyve21

Sujet: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.Synonyms: Zinc finger FYVE domain-containing protein 21

ID gène: 79038

NCBI Accession: NP_001185882