Myc Target 1 anticorps (C-Term)
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- Antigène Voir toutes Myc Target 1 (MYCT1) Anticorps
- Myc Target 1 (MYCT1)
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Myc Target 1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse, Rat.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- 17 amino acid synthetic peptide near the carboxy terminus of Human MYCT1
- Isotype
- IgG
- Top Product
- Discover our top product MYCT1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- Myc Target 1 (MYCT1)
- Autre désignation
- MYCT1 (MYCT1 Produits)
- Synonymes
- anticorps MYCT1, anticorps MGC147166, anticorps si:dkey-12h9.2, anticorps MTLC, anticorps 1110020B04Rik, anticorps AI225941, anticorps AI642973, anticorps Mtmc1, anticorps myc target 1, anticorps MYC target 1, anticorps myc target 1a, anticorps MYCT1, anticorps myct1, anticorps myct1a, anticorps Myct1
- Sujet
- MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.Synonyms: MTLC, MTMC1, Myc target protein 1
- Poids moléculaire
- 26 kDa
- ID gène
- 80177
- NCBI Accession
- NP_079383
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