TMEM59L anticorps (C-Term)

N° du produit ABIN1450042

Détail du produit anti-TMEM59L anticorps

Antigène: TMEM59L (Transmembrane Protein 59-Like (TMEM59L))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM59L est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid synthetic peptide near carboxy terminus of Human TMEM59L

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TMEM59L

Antigène: TMEM59L (Transmembrane Protein 59-Like (TMEM59L))

Autre désignation: TMEM59L (TMEM59L Produits)

Synonymes: anticorps LOC719572, anticorps BSMAP, anticorps C19orf4, anticorps 5330410G16Rik, anticorps RGD1305557, anticorps transmembrane protein 59 like, anticorps transmembrane protein 59-like, anticorps TMEM59L, anticorps Tmem59l

Sujet: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.Synonyms: BSMAP, Brain-specific membrane-anchored protein, C19orf4, Transmembrane protein 59-like

ID gène: 25789

NCBI Accession: NP_036241