DPAGT1 anticorps (N-Term)

N° du produit ABIN1450055

Détail du produit anti-DPAGT1 anticorps

Antigène: DPAGT1 (Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPAGT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid synthetic peptide near the amino terminus of Human DPAGT1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-DPAGT1 (ABIN1450055)

Niewiadomska, Janik, Perlińska-Lenart, Piłsyk, Palamarczyk, Kruszewska: "The role of Alg13 N-acetylglucosaminyl transferase in the expression of pathogenic features of Candida albicans." dans: Biochimica et biophysica acta. General subjects, Vol. 1861, Issue 4, pp. 789-801, (2017) (PubMed).

Détails sur DPAGT1

Antigène: DPAGT1 (Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1))

Autre désignation: DPAGT1 (DPAGT1 Produits)

Synonymes: anticorps AU021132, anticorps Dpagt2, anticorps GPT, anticorps Gnpta, anticorps DPAGT2, anticorps G1PT, anticorps GNPTA, anticorps GTR2, anticorps ALG7, anticorps CDG-Ij, anticorps CDG1J, anticorps CMSTA2, anticorps D11S366, anticorps DGPT, anticorps DPAGT, anticorps UAGT, anticorps UGAT, anticorps dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase), anticorps dolichyl-phosphate N-acetylglucosaminephosphotransferase 1, anticorps Dpagt1, anticorps DPAGT1

Sujet: The UDP-N-acetylglucosamine-dolichyl-phosphate N-acetyl-glucosaminephosphotransferase (DPAGT1) is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. Mutations in this integral endoplasmic reticulum (ER) membrane protein enzyme belongs to the glycosyltransferase family 4 results in the congenital disorder of glycosylation type Ij with symptoms such as severe hypotonia, medically intractable seizures, mental retardation, microcephaly, and exotropia. Recent experiments have shown that DPAGT1 is a target of the Wnt/beta-catenin signaling pathway, with Wnt3a inducing higher DPAGT1 mRNA expression.Synonyms: DPAGT2, G1PT, GPT, GlcNAc-1-P transferase, N-acetylglucosamine-1-phosphate transferase, UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase

ID gène: 1798

NCBI Accession: NP_001373