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SPINK7/ECRG2 anticorps (C-Term)
SPINK7
Reactivité: Humain, Souris, Rat
WB, IHC (p), EIA
Hôte: Poulet
Polyclonal
unconjugated
N° du produit ABIN1450063
Détail du produit anti-SPINK7/ECRG2 anticorps
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Antigène
Voir toutes SPINK7/ECRG2 (SPINK7) Anticorps
SPINK7/ECRG2 (SPINK7)
(Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7))
Épitope
Tous les épitopes à travers SPINK7/ECRG2 Anticorps.
C-Term
Reactivité
Toutes les réactivités sur SPINK7/ECRG2 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur SPINK7/ECRG2 Anticorps
Poulet
Clonalité
Toutes les clonalités sur SPINK7/ECRG2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers SPINK7/ECRG2 Anticorps
Cet anticorp SPINK7/ECRG2 est non-conjugé
Application
Tous les applications à travers SPINK7/ECRG2 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Réactivité croisée (Details)
Species reactivity (tested):Human, Mouse, Rat.
Purification
Affinity chromatography purified via peptide column
Immunogène
16 amino acid synthetic peptide near the carboxy terminus of Human ECRG2
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur SPINK7/ECRG2
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Antigène
SPINK7/ECRG2 (SPINK7)
(Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7))
Autre désignation
ECRG-2 (SPINK7 Produits )
Synonymes
anticorps Ecg2, anticorps Ecrg2, anticorps OM, anticorps ECG2, anticorps ECRG2, anticorps EG408198, anticorps serine peptidase inhibitor, Kazal type 7, anticorps serine peptidase inhibitor, Kazal type 7 (putative), anticorps Spink7, anticorps SPIK7, anticorps SPINK7
Sujet
The esophageal cancer-susceptibility gene 2 (ECRG2), also known as SPINK7, is a novel tumor suppressor gene identified from the human esophagus. It interacts directly with metallothionein 2A and urokinase-type plasminogen activator (uPA), and downregulates the activity of uPA, leading to reduced cancer cell migration, invasion and metastasis. ECRG2 forms a complex with uPA and its receptor uPAR, modifying the dynamic association of uPAR with beta1 integrins and disrupting the Src/MAP kinase pathway that normally stimulates cell migration and invasion. ECRG2 may thus represent a novel therapeutic target for cancer.Synonyms: ECG2, Esophagus cancer-related gene 2 protein, MGC133105, MGC133106, SPINK7, Serine protease inhibitor Kazal-type 7, UNQ745/PRO1474
ID gène
84651
Vus récemment
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