AFAP anticorps (N-Term)
-
- Antigène Voir toutes AFAP (AFAP1) Anticorps
- AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))
-
Épitope
- N-Term
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp AFAP est non-conjugé
-
Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- AFAP1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of Human AFAP1
- Isotype
- IgG
- Top Product
- Discover our top product AFAP1 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))
- Autre désignation
- AFAP1 (AFAP1 Produits)
- Synonymes
- anticorps afap, anticorps afap-110, anticorps AFAP, anticorps AFAP-110, anticorps AFAP110, anticorps 2600003E23Rik, anticorps 9630044L16Rik, anticorps AI848729, anticorps Afap, anticorps mKIAA3018, anticorps actin filament associated protein 1, anticorps AFAP1, anticorps afap1, anticorps Afap1
- Sujet
- The actin filament-associated protein AFAP1 (AFAP-110) is an actin cross-linking protein first identified as a substrate of the viral oncogene v-Src. AFAP1 has a fundamental role in actin cytoskeleton arrangement. It contains a carboxyterminal actin-binding domain that directly binds to F-actin and serves as an adaptor protein in the regulation of SRC and PKC signal transduction by several functional domains, including 2 pleckstrin homology (PH) domains, a Src homology 3-binding (SH3-binding) motif, and several SH2-binding motifs. It is overexpressed in prostate carcinoma and contributes to tumor growth by regulating cell-matrix adhesions and migration in the cancer cells. AFAP1 represent a possible therapeutic target for controlling tumorigenesis and metastasis.Synonyms: 110 kDa actin filament-associated protein, AFAP-110, Actin filament-associated protein 1
- ID gène
- 60312
- NCBI Accession
- NP_940997
-