GRB10 anticorps (C-Term)

N° du produit ABIN1450124

Détail du produit anti-GRB10 anticorps

Antigène: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRB10 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity Chromatography purified via peptide column

Immunogène: 17 amino acid synthetic peptide near the carboxy terminus of Human GRB10

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GRB10

Antigène: GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Autre désignation: GRB10 / GRBIR (GRB10 Produits)

Synonymes: anticorps grb10, anticorps zgc:91987, anticorps GRB10, anticorps grb-10, anticorps grb-ir, anticorps irbp, anticorps meg1, anticorps rss, anticorps LOC100224775, anticorps 5730571D09Rik, anticorps AI325020, anticorps Meg1, anticorps mKIAA0207, anticorps RGD1566234, anticorps GRB-IR, anticorps Grb-10, anticorps IRBP, anticorps MEG1, anticorps RSS, anticorps growth factor receptor bound protein 10, anticorps growth factor receptor-bound protein 10a, anticorps growth factor receptor bound protein 10 L homeolog, anticorps growth factor receptor-bound protein 10, anticorps GRB10, anticorps grb10a, anticorps grb10, anticorps grb10.L, anticorps LOC100434903, anticorps Grb10

Sujet: GRB10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules and function in diverse cellular processes. GRB10 is a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of GRB10 inhibits tyrosine kinase activity and results in growth suppression. GRB10 can also interact with the L isoform of the proapoptotic protein Bim. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts .Synonyms: Grb-IR, Growth factor receptor-bound protein 10, Insulin receptor-binding protein Grb-IR, KIAA0207

ID gène: 2887

NCBI Accession: NP_005302

Pathways: Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2