Nicalin anticorps (C-Term)

N° du produit ABIN1450143

Détail du produit anti-Nicalin anticorps

Antigène: Nicalin (NCLN)

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nicalin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: Multiple isoforms of NCLN are known to exist.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid synthetic peptide near the carboxy terminus of Human NCLN

Isotype: IgG

Information d'application

Indications d'application: Western blot: 1-2 μg/ml.
Positive Control: Mouse heart tissue lysate.
Immunofluorescence: Start at 2.5 μg/ml.
Immunohistochemistry on Paraffin Sections: Start at 2.5 μg/ml.

Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Nicalin

Antigène: Nicalin (NCLN)

Autre désignation: Nicalin (NCLN Produits)

Sujet: Nicalin, along with its binding partner Nomo, is a novel signaling antagonist to Nodals, signaling factors of the TGF-beta superfamily that play a key role in vertebrate development. Nicalin is distantly related to Nicastrin, a component of the Alzheimer’s disease-associated gamma-secretase, and is thought to have a similar function. Another protein, TMEM147, has also been recently identified as associating with Nicalin and NOMO as part of the gamma-secretase-like complex.
Synonyms: NCLN

ID gène: 56926

NCBI Accession: NP_064555

UniProt: Q969V3