TET2 anticorps (N-Term)
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- Antigène Voir toutes TET2 Anticorps
- TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TET2 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- 18 amino acid synthetic peptide near the amino terminus of Human TET2
- Isotype
- IgG
- Top Product
- Discover our top product TET2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
- Autre désignation
- TET2 (TET2 Produits)
- Synonymes
- anticorps KIAA1546, anticorps MDS, anticorps Ayu17-449, anticorps E130014J05Rik, anticorps mKIAA1546, anticorps RGD1311625, anticorps tet methylcytosine dioxygenase 2, anticorps TET2, anticorps Tet2
- Sujet
- TET2, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. It is a candidate tumor suppressor gene reported to be mutated in approximately 14 % of patients with JAK2V617F-positive myeloproliferative neoplasms, and can be mutated in other hematopoietic disorders such as myelodysplastic syndromes, acute myeloid leukemia, and chronic myelomonocytic leukemia. Analysis of the TET2 and JAK2 mutations in these neoplasms suggests that mutations in TET2 do not represent a predisposition for acquiring mutations in JAK2.Synonyms: KIAA1546, Methylcytosine dioxygenase TET2
- ID gène
- 54790
- NCBI Accession
- NP_001120680
- Pathways
- L'effet Warburg
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