GFRA1 anticorps
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- Antigène Voir toutes GFRA1 Anticorps
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
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Reactivité
- Humain
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Hôte
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Poulet
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GFRA1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Specificité
- Glial cell line-derived neurotrophic factor (GDNF) andneurturin (NTN) are two structurally related, potent neurotrophic factors thatplay key roles in the control of neuron survival and differentiation. The GFRa-1is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediatesactivation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674)
- Attributs du produit
- Mono- and polyclonal antibodies to human growth factors and neural growth factor receptors.
- Purification
- GFRa-1 affinity purified
- Isotype
- IgY
- Top Product
- Discover our top product GFRA1 Anticorps primaire
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- Indications d'application
- Westernimmunoblotting, recommended dilution 1:5 000 to 1:10 000, ELISA: 1:80 000 to160 000,IF 1:1000 to 1:2000. Polyclonal antibody working titer has to be established practically for each particularantigen and assay format
- Commentaires
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Synonym: RET ligand 1, TGF-beta related neurotrophic factorreceptor 1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml
- Buffer
- Concentrated ammonium sulphate in PBS pH 7.4
- Conseil sur la manipulation
- As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use
- Stock
- 4 °C
- Stockage commentaire
- This product is shipped in non-frozen liquid form in ambient conditions
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- Antigène
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
- Autre désignation
- GFRa-1 (GFRA1 Produits)
- Sujet
- Recombinant His-tagged human GFRa-1 protein producedusing CHO-based cell line. For production of hGFRa-1, glycosylphosphatidyl-inositol GPI-anchor was removedand protein was secreted to the cell culture supernatant. Protein was purifiedby Ni-affinity chromatography following gel-filtration from cell culturesupernatant
- UniProt
- P56159
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