DKC1 anticorps (AA 245-514)
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- Antigène Voir toutes DKC1 Anticorps
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
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Épitope
- AA 245-514
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DKC1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Séquence
- ELRRVRSGVM SEKDHMVTMH DVLDAQWLYD NHKDESYLRR VVYPLEKLLT SHKRLVMKDS AVNAICYGAK IMLPGVLRYE DGIEVNQEIV VITTKGEAIC MAIALMTTAV ISTCDHGIVA KIKRVIMERD TYPRKWGLGP KASQKKLMIK QGLLDKHGKP TDSTPATWKQ EYVDYSESAK KEVVAEVVKA PQVVAEAAKT AKRKRESESE SDETPPAAPQ LIKKEKKKSK KDKKAKAGLE SGAEPGDGDS DTTKKKKKKK KAKEVELVSE
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 245-514 of human DKC1 (NP_001354.1).
- Isotype
- IgG
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid freeze / thaw cycles
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
- Autre désignation
- DKC1 (DKC1 Produits)
- Synonymes
- anticorps CBF5, anticorps DKC, anticorps DKCX, anticorps NAP57, anticorps NOLA4, anticorps XAP101, anticorps dyskerin, anticorps fv62a07, anticorps wu:fa28f10, anticorps wu:fc87a02, anticorps wu:fi24a05, anticorps wu:fv62a07, anticorps zgc:110395, anticorps DKC1, anticorps cbf5, anticorps dkc, anticorps nap57, anticorps nola4, anticorps xap101, anticorps BC068171, anticorps Nap57, anticorps AtCBF5, anticorps AtNAP57, anticorps homologue of NAP57, anticorps dyskerin pseudouridine synthase 1, anticorps microRNA 664b, anticorps dyskeratosis congenita 1, dyskerin, anticorps dyskeratosis congenita 1, dyskerin L homeolog, anticorps homologue of NAP57, anticorps DKC1, anticorps MIR664B, anticorps dkc1, anticorps dkc1.L, anticorps Dkc1, anticorps NAP57
- Sujet
- This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.,DKC1,CBF5,DKC,DKCX,NAP57,NOLA4,XAP101,Epigenetics & Nuclear Signaling,RNA Binding,DKC1
- Poids moléculaire
- 47 kDa/57 kDa
- ID gène
- 1736
- UniProt
- O60832
- Pathways
- Telomere Maintenance
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