ERCC5 anticorps (AA 1-270)

N° du produit ABIN1512873

Détail du produit anti-ERCC5 anticorps

Antigène: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Épitope: AA 1-270

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC5 est non-conjugé

Application: Immunofluorescence (IF)

Séquence: MGVQGLWKLL ECSGRQVSPE ALEGKILAVD ISIWLNQALK GVRDRHGNSI ENPHLLTLFH RLCKLLFFRI RPIFVFDGDA PLLKKQTLVK RRQRKDLASS DSRKTTEKLL KTFLKRQAIK TAFRSKRDEA LPSLTQVRRE NDLYVLPPLQ EEEKHSSEEE DEKEWQERMN QKQALQEEFF HNPQAIDIES EDFSSLPPEV KHEILTDMKE FTKRRRTLFE AMPEESDDFS QYQLKGLLKK NYLNQHIEHV QKEMNQQHSG HIRRQYEDEG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ERCC5 (NP_000114.2).

Isotype: IgG

Information d'application

Indications d'application: IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ERCC5

Antigène: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Autre désignation: ERCC5 (ERCC5 Produits)

Synonymes: anticorps COFS3, anticorps ERCM2, anticorps UVDR, anticorps XPG, anticorps XPGC, anticorps cofs3, anticorps ercm2, anticorps uvdr, anticorps xpg, anticorps xpgc, anticorps Xpg, anticorps ERCC excision repair 5, endonuclease, anticorps excision repair cross-complementation group 5 L homeolog, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 5, anticorps ERCC5, anticorps ercc5.L, anticorps Ercc5

Sujet: This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.,ERCC5,COFS3,ERCC5-201,ERCM2,UVDR,XPG,XPGC,Epigenetics & Nuclear Signaling,DNA Damage & Repair,ERCC5

Poids moléculaire: 27 kDa/47 kDa/133 kDa

ID gène: 2073

UniProt: P28715

Pathways: Réparation de l'ADN