Haptoglobin anticorps
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- Antigène Voir toutes Haptoglobin (HP) Anticorps
- Haptoglobin (HP)
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Haptoglobin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human HP
- Isotype
- IgG
- Top Product
- Discover our top product HP Anticorps primaire
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- Indications d'application
- Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid freeze / thaw cycles
- Stock
- -20 °C/-80 °C
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- Antigène
- Haptoglobin (HP)
- Autre désignation
- HP (HP Produits)
- Synonymes
- anticorps HP, anticorps wu:fb64e01, anticorps BP, anticorps HP2ALPHA2, anticorps HPA1S, anticorps HP-1, anticorps HPR, anticorps Zonulin, anticorps haptoglobin, anticorps haptoglobin-like, anticorps HP, anticorps hp, anticorps Hp, anticorps LOC479668, anticorps LOC101102413
- Sujet
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This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohns disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinsons disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms: BP, HP2-ALPHA-2, HPA1S, MGC111141 - ID gène
- 3240
- UniProt
- P00738
- Pathways
- Transition Metal Ion Homeostasis
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