NeuN anticorps (AA 1-220)

N° du produit ABIN1513254

Détail du produit anti-NeuN anticorps

Antigène: NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))

Épitope: AA 1-220

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NeuN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MAQPYPPAQY PPPPQNGIPA EYAPPPPHPT QDYSGQTPVP TEHGMTLYTP AQTHPEQPGS EASTQPIAGT QTVPQTDEAA QTDSQPLHPS DPTEKQQPKR LHVSNIPFRF RDPDLRQMFG QFGKILDVEI IFNERGSKGF GFVTFETSSD ADRAREKLNG TIVEGRKIEV NNATARVMTN KKTGNPYTNG WKLNPVVGAV YGPEFYAVTG FPYPTTGTAV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NeuN (NP_001076044.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-NeuN (ABIN1513254)

Liu, Qin, Dai, Zhang, Xue, Ni, Han, Zhu, Yuan, Tao, Cao: "SMAD4 is Involved in the Development of Endotoxin Tolerance in Microglia." dans: Cellular and molecular neurobiology, Vol. 36, Issue 5, pp. 777-88, (2017) (PubMed).

Détails sur NeuN

Antigène: NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))

Autre désignation: RBFOX3 (RBFOX3 Produits)

Synonymes: anticorps FOX-3, anticorps FOX3, anticorps HRNBP3, anticorps NEUN, anticorps Fox-3, anticorps Hrnbp3, anticorps NeuN, anticorps Neuna60, anticorps Neun, anticorps RGD1560070, anticorps RNA binding fox-1 homolog 3, anticorps RNA binding protein, fox-1 homolog (C. elegans) 3, anticorps RNA binding protein, fox-1 homolog 3, anticorps RBFOX3, anticorps Rbfox3

Sujet: This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.,FOX-3,FOX3,HRNBP3,NEUN,NeuN,RBFOX3,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,Cell Type Marker,Neuron marker,RBFOX3

Poids moléculaire: 33 kDa/35 kDa

ID gène: 146713

UniProt: A6NFN3