PSME3 anticorps (AA 1-254)

N° du produit ABIN6213753

Détail du produit anti-PSME3 anticorps

Antigène: PSME3

Épitope: AA 1-254

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSME3 est non-conjugé

Application: Western Blotting (WB)

Séquence: MASLLKVDQE VKLKVDSFRE RITSEAEDLV ANFFPKKLLE LDSFLKEPIL NIHDLTQIHS DMNLPVPDPI LLTNSHDGLD GPTYKKRRLD ECEEAFQGTK VFVMPNGMLK SNQQLVDIIE KVKPEIRLLI EKCNTPSGKG PHICFDLQVK MWVQLLIPRI EDGNNFGVSI QEETVAELRT VESEAASYLD QISRYYITRA KLVSKIAKYP HVEDYRRTVT EIDEKEYISL RLIISELRNQ YVTLHDMILK NIEK

Réactivité croisée: Humain, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human PSME3 (NP_789839.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PSME3

Antigène: PSME3

Autre désignation: PSME3 (PSME3 Produits)

Synonymes: anticorps AA410043, anticorps AU020960, anticorps Ki, anticorps PA28gamma, anticorps REGgamma, anticorps pa28g, anticorps Ab2-371, anticorps PA28-gamma, anticorps PA28G, anticorps REG-GAMMA, anticorps psme3b, anticorps proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki), anticorps proteasome activator subunit 3, anticorps proteasome activator subunit 3 S homeolog, anticorps Psme3, anticorps PSME3, anticorps psme3.S

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Alternate splicing results in multiple transcript variants.,PSME3,HEL-S-283,Ki,PA28-gamma,PA28G,PA28gamma,REG-GAMMA,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Ubiquitin,Immunology & Inflammation,PSME3

Poids moléculaire: 29 kDa/30 kDa

ID gène: 10197

UniProt: P61289

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA