TSG101 anticorps (C-Term)

N° du produit ABIN1513646

Détail du produit anti-TSG101 anticorps

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSG101 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Séquence: SALEKMENQS ENNDIDEVII PTAPLYKQIL NLYAEENAIE DTIFYLGEAL RRGVIDLDVF LKHVRLLSRK QFQLRALMQK ARKTAGLSDL Y

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human TSG101/VPS23 (NP_006283.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-TSG101 (ABIN1513646)

Zhao, Wu, Duan, Ma, Shen, Wei, Cui, Zhang, Xie, Liu: "Quantitative proteomic analysis of exosome protein content changes induced by hepatitis B virus in Huh-7 cells using SILAC labeling and LC-MS/MS." dans: Journal of proteome research, Vol. 13, Issue 12, pp. 5391-402, (2015) (PubMed).

Yu, Yan, Yang, Wu, Ling, Chen, Tang, Tan, Cao, Wu, Yan, Wang: "Platelets promote tumour metastasis via interaction between TLR4 and tumour cell-released high-mobility group box1 protein." dans: Nature communications, Vol. 5, pp. 5256, (2014) (PubMed).

Détails sur TSG101

Antigène: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Autre désignation: TSG101 (TSG101 Produits)

Synonymes: anticorps CG9712, anticorps DmTSG101, anticorps Dmel\\CG9712, anticorps ESCRT-I, anticorps Tsg101, anticorps burs, anticorps dTSg101, anticorps dTsg101, anticorps dVps23, anticorps ept, anticorps tsg101, anticorps vps23, anticorps TSG101, anticorps MGC76193, anticorps TSG10, anticorps VPS23, anticorps AI255943, anticorps CC2, anticorps Rw, anticorps zgc:86926, anticorps tumor susceptibility 101, anticorps Tumor susceptibility gene 101, anticorps Tumor Susceptibility Gene homolog, anticorps tumor susceptibility gene 101, anticorps tumor susceptibility 101a, anticorps tumor susceptibility 101 L homeolog, anticorps TSG101, anticorps tsg-101, anticorps tsg101, anticorps Tsg101, anticorps tsg101a, anticorps tsg101.L

Sujet: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.,TSG10,VPS23,TSG101 / VPS23,TSG101,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cell differentiation,TSG101

Poids moléculaire: 31 kDa/43 kDa

ID gène: 7251

UniProt: Q99816