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WFS1 anticorps (AA 1-285)

WFS1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1513689
  • Antigène Voir toutes WFS1 Anticorps
    WFS1 (Wolfram Syndrome 1 (WFS1))
    Épitope
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-285
    Reactivité
    • 30
    • 8
    • 5
    • 1
    Humain
    Hôte
    • 30
    • 1
    • 1
    Lapin
    Clonalité
    • 31
    • 1
    Polyclonal
    Conjugué
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WFS1 est non-conjugé
    Application
    • 26
    • 13
    • 13
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Séquence
    MDSNTAPLGP SCPQPPPAPQ PQARSRLNAT ASLEQERSER PRAPGPQAGP GPGVRDAAAP AEPQAQHTRS RERADGTGPT KGDMEIPFEE VLERAKAGDP KAQTEVGKHY LQLAGDTDEE LNSCTAVDWL VLAAKQGRRE AVKLLRRCLA DRRGITSENE REVRQLSSET DLERAVRKAA LVMYWKLNPK KKKQVAVAEL LENVGQVNEH DGGAQPGPVP KSLQKQRRML ERLVSSESKN YIALDDFVEI TKKYAKGVIP SSLFLQDDED DDELAGKSPE DLPLR
     Réactivité croisée
    Humain, Souris
    Attributs du produit
    Polyclonal Antibodies
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human WFS1 (NP_001139325.1).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze / thaw cycles
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    WFS1 (Wolfram Syndrome 1 (WFS1))
    Autre désignation
    WFS1 (WFS1 Produits)
    Synonymes
    anticorps WFRS, anticorps WFS, anticorps WFSL, anticorps CG4917, anticorps Dmel\\CG4917, anticorps GB15257, anticorps WFS1, anticorps AI481085, anticorps wolframin, anticorps wfs1, anticorps wolframin ER transmembrane glycoprotein, anticorps wolfram syndrome 1, anticorps wolframin, anticorps Wolfram syndrome 1 (wolframin) L homeolog, anticorps Wfs1, anticorps WFS1, anticorps wfs1, anticorps LOC552818, anticorps CpipJ_CPIJ013087, anticorps wfs1.L
    Sujet
    This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.,WFS1,CTRCT41,WFRS,WFS,WFSL,wolframin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Insulin and insulin-like,Endocrine & Metabolism,Endocrine and metabolic diseases,Metabolic disorders,Neuroscience,WFS1
    Poids moléculaire
    100 kDa
    ID gène
    7466
    UniProt
    O76024
    Pathways
    Sensory Perception of Sound, Carbohydrate Homeostasis, ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome
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