This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This PER1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1156-1183 amino acids from the C-terminal region of human PER1.
PER1
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
PER1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
Date de péremption
6 months
Hwang-Verslues, Chang, Jeng, Kuo, Chiang, Chang, Hsieh, Su, Lin, Abbondante, Yang, Hsu, Yu, Chang, Shew, Lee, Lee: "Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 30, pp. 12331-6, (2013) (PubMed).
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. Alternative splicing has been observed in this gene, however, these variants have not been fully described.