This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This TTDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-177 amino acids from the C-terminal region of human TTDN1.
The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.