Kallikrein 2 anticorps (C-Term)

N° du produit ABIN1536788

Détail du produit anti-Kallikrein 2 anticorps

Antigène: Kallikrein 2 (KLK2)

Épitope: AA 166-197, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This Kallikrein 2 (KLK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-197 amino acids from the C-terminal region of human Kallikrein 2 (KLK2).

Clone: RB06101

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Kallikrein 2 (ABIN1536788)

Guihard, Yao, Blazquez-Medela, Iruela-Arispe, Boström, Yao: "Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2Akita/+ Mice." dans: PLoS ONE, Vol. 11, Issue 12, pp. e0167936, (2017) (PubMed).

Détails sur Kallikrein 2

Antigène: Kallikrein 2 (KLK2)

Abstract: KLK2 Produits

Synonymes: anticorps KLK2A2, anticorps hGK-1, anticorps hK2, anticorps KLK2, anticorps Ton, anticorps rGK-2, anticorps Klk2, anticorps kallikrein related peptidase 2, anticorps kallikrein-related peptidase 2, anticorps kallikrein-2, anticorps kallikrein 1-related peptidase C2, anticorps KLK2, anticorps LOC748637, anticorps Klk1c2, anticorps LOC100716976

Sujet: Kallikreins are a group of serine proteases manifesting diverse physiological functions. The glandular kallikreins are a distinct group of serine proteases with an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Many kallikrein genes are differentially expressed in various malignancies. Human glandular kallikrein (hK2, encoded by the KLK2 gene) is an emerging tumor marker for prostate cancer.

Poids moléculaire: 28671

ID gène: 3817

NCBI Accession: NP_001002231, NP_001243009, NP_005542

UniProt: P20151

Pathways: Système du Complément