This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This CHMP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-204 amino acids from the C-terminal region of human CHMP5.
anticorps SNF7DC2, anticorps cgi-34, anticorps hspc177, anticorps pnas-2, anticorps vps60, anticorps chmp5, anticorps zgc:64125, anticorps C9orf83, anticorps HSPC177, anticorps PNAS-2, anticorps Vps60, anticorps 2210412K09Rik, anticorps AW545668, anticorps RGD1305968, anticorps charged multivesicular body protein 5 S homeolog, anticorps charged multivesicular body protein 5b, anticorps charged multivesicular body protein 5, anticorps charged multivesicular body protein 5 L homeolog, anticorps chromatin modifying protein 5, anticorps chmp5.S, anticorps chmp5b, anticorps CHMP5, anticorps chmp5.L, anticorps chmp5, anticorps Chmp5
Sujet
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).