HUS1 anticorps (C-Term)

N° du produit ABIN1536829

Détail du produit anti-HUS1 anticorps

Antigène: HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

Épitope: AA 199-226, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HUS1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HUS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-226 amino acids from the C-terminal region of human HUS1.

Clone: RB36257

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: HUS1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur HUS1

Antigène: HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

Autre désignation: HUS1 (HUS1 Produits)

Synonymes: anticorps hHUS1, anticorps mHus1, anticorps XHus1, anticorps hus1, anticorps HUS1 checkpoint clamp component, anticorps checkpoint clamp complex protein Hus1, anticorps HUS1 checkpoint clamp component L homeolog, anticorps HUS1, anticorps Hus1, anticorps hus1, anticorps hus1.L

Sujet: The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. [provided by RefSeq].

Poids moléculaire: 31691

ID gène: 3364

NCBI Accession: NP_004498

UniProt: O60921