NTAN1 anticorps (C-Term)

N° du produit ABIN1536839

Détail du produit anti-NTAN1 anticorps

Antigène: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Épitope: AA 203-230, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NTAN1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NTAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the C-terminal region of human NTAN1.

Clone: RB37947

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: NTAN1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur NTAN1

Antigène: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Autre désignation: NTAN1 (NTAN1 Produits)

Synonymes: anticorps PNAA, anticorps PNAD, anticorps N-terminal Asn amidase, anticorps N-terminal asparagine amidase, anticorps Ntan1, anticorps NTAN1

Sujet: Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position (By similarity).

ID gène: 123803

NCBI Accession: NP_001257695, NP_001257696, NP_775745

UniProt: Q96AB6