Septin 2 anticorps (C-Term)

N° du produit ABIN1537024

Détail du produit anti-Septin 2 anticorps

Antigène: Septin 2 (SEPT2)

Épitope: AA 280-309, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 2 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SEPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human SEPT2.

Clone: RB36619

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: SEPT2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur Septin 2

Antigène: Septin 2 (SEPT2)

Autre désignation: SEPT2 (SEPT2 Produits)

Synonymes: anticorps DIFF6, anticorps NEDD5, anticorps Pnutl3, anticorps hNedd5, anticorps AW208991, anticorps Nedd-5, anticorps Nedd5, anticorps mKIAA0158, anticorps Vesp11, anticorps nedd5, anticorps wu:fb52g01, anticorps wu:fb99a01, anticorps Septin-2A, anticorps Septin-A, anticorps diff6, anticorps pnutl3, anticorps sept2, anticorps septa, anticorps xlsepta, anticorps SEPT2, anticorps Sep-02, anticorps Septin-2B, anticorps hnedd5, anticorps sept2-B, anticorps Septin-2, anticorps septin 2, anticorps septin 2 L homeolog, anticorps septin 2-like, anticorps COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain, anticorps septin 2 S homeolog, anticorps SEPT2, anticorps Sept2, anticorps sept2, anticorps sept2.L, anticorps SEPT2L, anticorps sepT2, anticorps sept2.S

Sujet: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Poids moléculaire: 41487

ID gène: 4735

NCBI Accession: NP_001008491, NP_001008492, NP_004395, NP_006146

UniProt: Q15019