This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This GTF3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-334 amino acids from the C-terminal region of human GTF3A.
anticorps 2010015D03Rik, anticorps 2610111I01Rik, anticorps 5330403M05Rik, anticorps GTF3A, anticorps TFIIIA, anticorps gtf3a, anticorps zgc:111799, anticorps AP2, anticorps general transcription factor III A, anticorps general transcription factor IIIA, anticorps general transcription factor 3A L homeolog, anticorps general transcription factor IIIAa, anticorps Gtf3a, anticorps GTF3A, anticorps gtf3a.L, anticorps gtf3aa
Sujet
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq].