This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SERPINI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-401 amino acids from the C-terminal region of human SERPINI2.
anticorps Spi14, anticorps MEPI, anticorps PANCPIN, anticorps PI14, anticorps TSA2004, anticorps serpin family I member 2, anticorps serpin peptidase inhibitor, clade I (pancpin), member 2 L homeolog, anticorps serpin peptidase inhibitor, clade I (pancpin), member 2, anticorps serine (or cysteine) peptidase inhibitor, clade I, member 2, anticorps SERPINI2, anticorps serpini2.L, anticorps Serpini2
Sujet
The protein encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.