SOCS7 anticorps (C-Term)

N° du produit ABIN1537362

Détail du produit anti-SOCS7 anticorps

Antigène: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Épitope: AA 458-486, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS7 est non-conjugé

Application: Western Blotting (WB)

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SOCS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-486 amino acids from the C-terminal region of human SOCS7.

Clone: RB37084

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: SOCS7 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur SOCS7

Antigène: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Autre désignation: SOCS7 (SOCS7 Produits)

Synonymes: anticorps NAP4, anticorps NCKAP4, anticorps SOCS4, anticorps SOCS6, anticorps 2310063P06Rik, anticorps C85125, anticorps Nap4, anticorps GB13951, anticorps zgc:175115, anticorps SOCS7, anticorps socs7, anticorps suppressor of cytokine signaling 7, anticorps suppressor of cytokine signaling, anticorps SOCS7, anticorps Socs7, anticorps LOC413772, anticorps socs7

Sujet: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Poids moléculaire: 62969

ID gène: 30837

NCBI Accession: NP_055413

UniProt: O14512