This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This GOLGA6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-543 amino acids from the C-terminal region of human GOLGA6A.
anticorps GLP, anticorps GOLGA6, anticorps golgin A6 family member A, anticorps GOLGA6A
Sujet
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. The protein encoded by this gene is a member of the golgin family of proteins, whose members localize to the Golgi. This gene is found in a large, low copy repeat sequence or duplicon that is found in multiple copies, that are greather than 90 % similar, on chromosome 15. Duplicons are associated with deletions, inversions and other chromosome rearrangements that underlie genomic disease. The protein encoded by this gene is thought to be a functional golgin protein while the majority of the related copies of this gene are thought to be transcribed pseudogenes.