This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This FIGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 615-643 amino acids from the C-terminal region of human FIGN.
Fidgetin is a member of the 'meiotic' or subfamily-7 group of ATPases associated with diverse cellular activities (AAA proteins). Fidgetin can interact with itself and this interaction can be abolished by truncating either the N- or C-terminus of the protein. AAA proteins are molecular chaperones that facilitate membrane fusion, proteolysis, peroxisome biogenesis, endosome sorting and meiotic spindle formation.