This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This PANX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-677 amino acids from the C-terminal region of human PANX2.
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene.