This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This TBC1D10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human TBC1D10B.
anticorps TBC1D10B, anticorps EPI64B, anticorps 1110003P22Rik, anticorps C87963, anticorps RGD1309191, anticorps TBC1 domain family member 10B, anticorps TBC1 domain family, member 10b, anticorps TBC1D10B, anticorps Tbc1d10b
Sujet
Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs, see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).