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TNNT3 anticorps (C-Term)

TNNT3 Reactivité: Humain WB Hôte: Lapin Polyclonal RB36783 unconjugated
N° du produit ABIN1537681
  • Antigène Voir toutes TNNT3 Anticorps
    TNNT3 (Fast Skeletal Troponin T (TNNT3))
    Épitope
    • 11
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 217-245, C-Term
    Reactivité
    • 40
    • 10
    • 9
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 28
    • 10
    • 2
    Lapin
    Clonalité
    • 32
    • 8
    Polyclonal
    Conjugué
    • 22
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TNNT3 est non-conjugé
    Application
    • 31
    • 17
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This TNNT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-245 amino acids from the C-terminal region of human TNNT3.
    Clone
    RB36783
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TNNT3 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    TNNT3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Date de péremption
    6 months
  • Antigène
    TNNT3 (Fast Skeletal Troponin T (TNNT3))
    Autre désignation
    TNNT3 (TNNT3 Produits)
    Synonymes
    anticorps fTnT, anticorps tnnt3a, anticorps TNTF, anticorps TnTf, anticorps Tnt, anticorps Tnnt3, anticorps troponin T3, fast skeletal type, anticorps troponin T3, skeletal, fast, anticorps troponin T3, fast skeletal type S homeolog, anticorps troponin T type 3 (skeletal, fast), anticorps troponin T1, slow skeletal type, anticorps TNNT3, anticorps Tnnt3, anticorps tnnt3.S, anticorps TNNT1
    Sujet
    The binding of Ca(2+) to the trimeric troponin complex initiates the process of muscle contraction. Increased Ca(2+) concentrations produce a conformational change in the troponin complex that is transmitted to tropomyosin dimers situated along actin filaments. The altered conformation permits increased interaction between a myosin head and an actin filament which, ultimately, produces a muscle contraction. The troponin complex has protein subunits C, I, and T. Subunit C binds Ca(2+) and subunit I binds to actin and inhibits actin-myosin interaction. Subunit T binds the troponin complex to the tropomyosin complex and is also required for Ca(2+)-mediated activation of actomyosin ATPase activity. There are 3 different troponin T genes that encode tissue-specific isoforms of subunit T for fast skeletal-, slow skeletal-, and cardiac-muscle. This gene encodes fast skeletal troponin T protein, also known as troponin T type 3. Alternative splicing results in multiple transcript variants encoding additional distinct troponin T type 3 isoforms. A developmentally regulated switch between fetal/neonatal and adult troponin T type 3 isoforms occurs. Additional splice variants have been described but their biological validity has not been established. Mutations in this gene may cause distal arthrogryposis multiplex congenita type 2B (DA2B).
    Poids moléculaire
    31825
    ID gène
    7140
    NCBI Accession
    NP_001036245, NP_001036246, NP_001036247, NP_006748
    UniProt
    P45378
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