This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SIRPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-134 amino acids from the Central region of human SIRPB1.
anticorps CD172b, anticorps SIRP-BETA-1, anticorps SIRPB1, anticorps SIRPG, anticorps signal regulatory protein beta 1, anticorps signal-regulatory protein beta-1, anticorps signal-regulatory protein beta-1 isoform 3, anticorps SIRPB1, anticorps LOC458036, anticorps LOC458430, anticorps LOC485809, anticorps LOC715912, anticorps LOC100458151
Sujet
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].